ARIA Workshop

Evolving Targeted Therapies for Cancer

Wednesday, November 2, 2022

TimeEventLeadPosition
8:00-8:15 amWelcome and Introductory RemarksSusan Hubbard Sandra DavernIn Person DJ Nelson Auditorium 1505, 182
8:15-8:55 amSubclonal Hypermutation: A Driver of Therapy Resistance in HER2+/ER+ Breast CancerRobert Beckman & Rebecca Riggins (Joint Presentation)Virtual DJ Nelson Auditorium 1505, 182
8:55-9:20 amIncorporation of physiologically relevant in-vitro models for cancer researchRebeca San MartinIn Person DJ Nelson Auditorium 1505, 182
9:20-9:45 amThe Combination of Radiation Therapy and Immunotherapy: Current and Future PerspectivesQuaovi SodjiIn Person DJ Nelson Auditorium 1505, 182
9:45-10:10 amPoly(Lactic-co-Glycolic Acid) Nanoparticles as Delivery Platforms for Actinium-225Miguel Toro GonzalezIn Person DJ Nelson Auditorium 1505, 182
10:10-10:25 amBreakBreakDJ Nelson Auditorium 1505, 182
10:25-10:50 amCancer Theranostics with (Intrinsically) Radiolabeled NanomaterialsWeibo CaiIn Person DJ Nelson Auditorium 1505, 182
10:50-11:15 amNuclear recoil effect in targeted alpha therapy - do we need to concern about it?Ján KozempelIn Person DJ Nelson Auditorium 1505, 182
11:15-11:40 amExosome-mediated targeting therapy of breast cancerYong JiangVirtual DJ Nelson Auditorium 1505, 182
11:40-12:10 pmPanel DiscussionPresenters will lead discussionDJ Nelson Auditorium 1505, 182
12:10-1:10 pmWorking Lunch:  Tri-Lab Accelerator Produced Ac-225Andrew BurgoyneDJ Nelson Auditorium 1505, 182
1:10-1:40 pmPredicting patient specific outcomes via imaging-based mathematical modelsThomas YankeelovVirtual DJ Nelson Auditorium 1505, 182
1:40-2:05 pmPolyazamacrocycle Ligands as Zirconium-89 Chelators: Teaching Old Dogs New TricksThaddeus J. WaddasVirtual DJ Nelson Auditorium 1505, 182
2:05-2:30 pmLead-Specific Chelator Enhances Targeted Alpha-Particle Radiotherapy of [212Pb]VMT-α-NET for SSTR2 Positive Tumors in MiceDijie LiuVirtual DJ Nelson Auditorium 1505, 182
2:30-2:55 pmComputational modeling of humans for medicine and beyondEhsan SamiIn Person DJ Nelson Auditorium 1505, 182
2:55-3:10 pmAfternoon BreakDJ Nelson Auditorium 1505, 182
3:10-3:35 pmA multiscale computational framework for precision dosimetry for radiation therapyGreeshma AgasthyaIn Person DJ Nelson Auditorium 1505, 182
3:35-4:00 pmCombination of carriers with complementary intratumoral microdistributions of delivered alpha-particles may realize the promise for Actinium-225 in large, solid tumorsStavroula SofouIn Person DJ Nelson Auditorium 1505, 182
4:00-4:25 pmDevelopment and Implementation of Expanded Macrocyclic Chelators for Targeted Radionuclide TherapyPaden KingIn Person DJ Nelson Auditorium 1505, 182
4:25-5:00 pmPanel DiscussionPresenters will lead discussionDJ Nelson Auditorium 1505, 182
5:00-5:15 PMRelocate to 5100 lobbyDJ Nelson Auditorium 1505, 182 to building 5100 lobby

Thursday, November 3, 2022

TimeEventProfileLocation
8:00-8:10 amIntroductory RemarksBalendra Sutharshan Sandra DavernIn Person DJ Nelson Auditorium 1505, 182
8:10-8:35 amRadiometals in Theranostics: From Chelate Chemistry to in vivo StudiesCarolyn J. AndersonVirtual DJ Nelson Auditorium 1505, 182
8:35-9:00 amLeveraging Bioorthogonal Chemistry to Improve RadiopharmaceuticalsBrian ZeglisIn Person DJ Nelson Auditorium 1505, 182
9:00-9:25 am“Radiobodies”: Nanobodies as molecular constructs for precision medicineMircea PodarIn Person DJ Nelson Auditorium 1505, 182
9:25-9:50 amMonte Carlo simulations for radiation biology and dosimetry in radiopharmaceutical therapyAlejandro Bertolet ReinaIn Person DJ Nelson Auditorium 1505, 182
9:50-10:15 amChelation Platform Development for Emerging Medical Radionuclides at Oak Ridge National LaboratoryNikki ThieleIn Person DJ Nelson Auditorium 1505, 182
10:15-10:30 amBreakDJ Nelson Auditorium 1505, 182
10:30-10:55 amDose point kernels and their potential application in labeling FAPI-compoundsAshok TiwariIn Person DJ Nelson Auditorium 1505, 182
10:55-11:20 amMetal Chelates & Multimers in Medical Probe DesignJohannes NotniVirtual DJ Nelson Auditorium1505, 182
11:20-11:45 amSiderocalin: A Universal Platform for RadiotherapeuticsJennifer WackerIn Person DJ Nelson Auditorium 1505, 182
11:45-12:20 pmPanel DiscussionPresenters will lead discussionDJ Nelson Auditorium 1505, 182
12:20-1:20 pmWorking Lunch:  The Radioisotope Program at Oak Ridge National LaboratoryRoy CoppingDJ Nelson Auditorium 1505, 182
1:30-5:00 pmORNL Tours (optional)
  • High Flux Isotope Reactor
  • Radiochemical Engineering Development Center (Hot Cells)
  • Graphite Reactor
  • Frontier Supercomputer
ORNL Tour HostsDifferent Locations
5:00 pmAdjournDepart ORNL